NextStar is the fastest-acting 30-day topical protection available* to help your pet fight off fleas and ticks. Our formula provides a monthly fast-acting, long-lasting solution to continue to protect your pet from fleas and ticks. NextStar is an easy-to-use, waterproof topical that kills and protects against fleas and ticks through contact with no bite required. Apply NextStar directly onto your pets skin for protection that starts working against fleas & ticks in 5 minutes, full nose-to-tail protection can take up to 24 48 hours after initial application.