Jones’ 4 Center Bones are cut from beef femur or beef tibia bones, dipped in natural liquid smoke and oven-roasted to perfection. These bones will have some bits of succulent marrow in the middle of the bone along with tasty meaty pieces left on the bone. They are USA natural beef femur or tibia bones with no artificial ingredients. These are best for small to medium size dogs. All Jones products are raised, sourced and hand-crafted in the USA. Ingredients: Beef Bone, Guaranteed Analysis: Crude Protein Min. 24%, Crude Fat Min. 22%, Crude Fiber Max. 1%, Moisture Max. 3%